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  Scar Remover Kit
 
 
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Product Code: SCARS1
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Description Instructions Ingredients
 
0.5 ounces sealed bottle. This kit is good for about 50 scars.
EXCELLENT for: Pitted scars, Scars, Acne scars, Rolling scars.
 
Features
  • TCA cross method used by plastic surgeons & dermatologists worldwide


  • -Pitted scars

  • -Scars

  • -Acne scars

  • -Rolling scars





    BACKGROUND: Acne

  • scarring is a common complication of acne and yet no appropriate
  • and effective single treatment modality has been developed.
  • We suggest a technique consisting of the focal application of higher
  • trichloroacetic acid (TCA) concentrations by pressing hard
  • on the entire depressed area of atrophic acne scars. This technique
  • is called chemical reconstruction of skin scars (CROSS) by
  • the authors.

  • OBJECTIVE: To evaluate the clinical effects of

  • CROSS on atrophic acne scars in dark-complexioned patients.

  • METHODS: An analysis was conducted of 65 patients

  • with atrophic acne scars who were treated with CROSS in our
  • hospitals between July 1996 and July 2001. Thirty-three patients
  • were treated with 65% TCA CROSS and 32 patients were treated with
  • 100% TCA CROSS. All patients had Fitzpatrick skin types N-V.

  • RESULTS: Patient treatment data indicated that

  • 27 of 33 patients (82%) (the 65% TCA group) and 30 of 32 patients
  • (94%) (the 100% TCA group) experienced a good clinical response.
  • All patients in the 100% TCA group who received five or six courses
  • of treatment showed excellent results. Good satisfaction rates
  • in the 65% and 100% TCA groups were re_ corded. There were no cases
  • of significant complication.

  • CONCLUSION: CROSS is a safe and very effective

  • single modality for the treatment of atrophic acne scars with
  • no significant complications.
    J. B. LEE, MD, W. G. CHUNG, MD, H.
  • KWAHCK, MD, AND K. H. LEE, MD HAVE INDICATED NO SIGNIFICANT INTEREST
  • WITH COMMERCIAL SUPPORTERS.

  • TRICHLOROACETIC ACID (TCA) has a particularly long history as an

  • effective agent for rendering histologic and clinical improvement
  • to the skin and is particularly safe when used as a superficial
  • peel or in "combination peels" of medium depth for acne
  • scars.l-4 Application of TCA to the skin causes precipitation of
  • proteins and coagulative necrosis of cells in the epidermis
  • and necrosis of collagen in the papillary to upper reticular dermis.1
  • Over several days the necrotic layers slough and the skin reepithelializes
  • from the adnexal structures that were spared from chemical damage.3
  • Dermal collagen remodeling after chemical peel may continue for
  • several months.4 Many investigators have observed that the clinical
  • effects of TCA were due to both a reorganization in dermal structural
  • elements and an increase in dermal volume as a result of an increase
  • in collagen content, glycosaminoglycan, and elastin.

  • Recent studies have shown that the reticular dermis heals with

  • scarring. They offer an explanation for some of the increased risk
  • associated with the use of TCA for deeper peels, suggesting that
  • peeling with higher TCA concentrations is very risky and definitely
  • not recommended.8 We also have limited experience and very little
  • information regarding the effects of higher TCA concentrations for
  • acne scars in darkcomplexioned patients, including Koreans
  • (types IVVI), whose skin is known to develop postinlammatory
  • hyperpigmentation.

  • In order to maximize the effects of TCA and to overcome complications

  • such as scarring, hyperpigmentation, and hypopigmentation,
  • we suggest a technique consisting of the focal application
  • of higher TCA concentrations by pressing hard on the entire depressed
  • area of atrophic acne scars using a sharpened wooden applicator
  • (Figure 1).11 Eventually it produces multiple, frosted white spots
  • on each acne scar (Figure 2). This technique is called chemical
  • reconstruction of skin scars (CROSS) by the authors; however, the
  • technique itself has not been patented or restricted to prevent
  • usage. The CROSS method, achieved with 65% or 100% TCA alone, has
  • the advantage of reconstructing acne scars by focusing on the
  • dermal thickening and collagen production that increase with high
  • TCA concentrations.7 Healing is more rapid and has a lower complication
  • rate than conventional full-face medium to deep chemical resurfacing,
  • because the adjacent normal tissue and adnexal structures are
  • spared. This technique does not involve the classic full-face
  • chemical resurfacing, but rather it can be used on focal chemical
  • scar reconstruction. We have used this technique successfully
  • for treating facial acne scars and dilated pores for the past 10
  • years. The purpose of this study was to evaluate the clinical effects
  • of the CROSS method on atrophic acne scars in dark-complexioned
  • patients.

  • Materials and Methods:

  • An analysis was conducted of 65 patients with atrophic
  • acne scars who were treated with the CROSS method in our hospitals
  • between July 1996 and July 2001. The CROSS method consists of the
  • focal application of higher TCA concentrations by pressing
  • hard on the entire depressed area of atrophic acne scars using a
  • sharpened wooden applicator (Figure 1). TCA, 65-100% weight/volume,
  • unbuffered, was made to order by a local pharmacy.

  • The patients' ages ranged from 25 to 45 years (mean 32.5 years).

  • Fifty-five patients were women and 10 were men. All patients had
  • Fitzpatrick skin types IV-V. Thirtythree patients were treated
  • with 65% TCA CROSS and 32 with 100% TCA CROSS.

  • For independent clinical assessment, two blinded physicians

  • evaluated the photographs taken before treatment and 6 months after
  • completion of the treatment. Physicians categorized the improvement
  • as follows: excellent, improvement greater than 70%; good, improvement
  • of 50-70%; fair, improvement of 30-50%; poor, improvement less
  • than 30%. The patient satisfaction rates were recorded from the
  • interviews conducted 6 months after the last treatment. The
  • physicians evaluated complications such as persistent erythema,
  • permanent hyperpigmentation, hypopigmentation, herpes simplex flare-up,
  • scarring, or keloids.

  • Patients were evaluated carefully before treatment about the factors

  • considered important, including the patients' current and past medications
  • and active acne lesion. Relevant history was obtained, including
  • any history of prior hypertrophic scarring, keloids, allergies,
  • or herpes simplex infection. Before CROSS, pretreatments such
  • as tretinoin cream were not applied because of the risk of unpredictable
  • and excessive TCA penetration.

  • Local anesthetics or sedation were not needed for CROSS. Patients

  • were comfortable during the procedure. After facial washing with
  • soap, the skin was cleansed with alcohol. And then either 65% TCA
  • or 100% TCA was focally applied by pressing hard on the entire depressed
  • area of atrophic acne scars using a sharpened wooden applicator
  • (Figure 1). The skin was monitored carefully until it reached a
  • "frosted" appearance after a single application.
  • The frosted appearance is the result of coagulation of epidermal
  • and dermal proteins and is used mainly to monitor the peel depth.
  • Focal application of TCA produced even frosted spots on each
  • acne scar within 10 seconds (Figure 2). After CROSS, an ointment
  • based antibiotic instead of an occlusive dressing was applied for
  • moisturizing effect, but this application was discontinued after
  • crust formation in order to avoid the risk of detaching the crust.
  • Oral prophylaxis consisting of antibiotics and antiviral medications
  • were not needed after CROSS. One to 2 weeks after CROSS, a moisturizer
  • sunscreen cream consisting of 0.05% tretinoin, 5% hydroquinone,
  • and a hydro base was used in some patients for a minimum of 4 weeks.
  • The application of makeup was allowed after CROSS. CROSS was
  • repeatedly performed every 1-3 months to allow dermal thickening
  • and collagen production.

  • Results:

  • The patient treatment data indicated that 27 of 33 patients
  • (82%) (the 65% TCA group) and 30 of 32 patients (94%) (the
  • 100% TCA group) experienced a good clinical response (Table 1).
  • In the 65% TCA group, 15 of 15 patients (100%) who received more
  • than six courses of treatment demonstrated good or excellent results,
  • as did 2 of 5 patients (40%) who received treatment three times
  • (Table 1 and Figure 3). Of interest is that all patients in the
  • 100% TCA group who received five or six courses of treatment showed
  • excellent results (Table 1 and Figure 4). Table 1 shows that the
  • clinical effects of 100% TCA CROSS were better than those of 65%
  • TCA CROSS.

  • Good satisfaction rates in the 65% and 100% TCA groups were recorded

  • in 27 of 33 patients (82%) and 30 of 32 patients (94%), respectively
  • (Table 2). In the 65% TCA group, 16 of 33 patients (49%) and 11
  • of 33 patients (33 %) were satisfied with this therapy absolutely
  • and moderately, respectively (Table 2). In the 100% TCA group, 19
  • of 32 patients (59%) and 11 of 34 patients (34%) were satisfied
  • absolutely and moderately, respectively (Table 2).

  • There were no cases of significant complication at the treatment

  • sites such as persistent erythema, permanent hyperpigmentation,
  • hypopigmentation, herpes simplex flare-up, scarring, or keloids.
  • Relative to the 65% TCA CROSS treatment, 100% TCA CROSS did not
  • increase the frequency of complications. Only mild erythema, which
  • faded over 2-8 weeks, and transient postinflammatory hyperpigmentation,
  • which disappeared over 6 weeks, occurred. Mild pustular eruptions
  • occurred in only four patients and cleared within 1 week with the
  • use of cefadroxil500 mg three times a day. The two patients who
  • received isotretinoin for 3 months before treatment showed good
  • results without excessive scarring, although it should be noted
  • that full-face medium to deep chemical resurfacing is relatively
  • contraindicated in patients who have taken isotretinoin within the
  • previous 6 months because of the increased risk of hypertrophic
  • scarring.

  • The results indicated that higher treatment frequency of CROSS

  • application on acne scars improved the therapeutic effect, and there
  • were no significant complications. Furthermore, application of a
  • higher TCA concentration was more effective in the treatment
  • of atrophic acne scars.
  • Discussion:

  • Acne is a chronic inflammatory disease of the pilosebaceous unit

  • and a condition commonly experienced in adolescents, but recent
  • data indicate that the prevalence of clinical acne does not
  • show a significant decrease in women between the ages of 25
  • and 44 years.12 Acne scars are more common in this persistent acne
  • group, because acne scars correlate with the duration of acne. Minor
  • acne scarring may occur in up to 95% of patients, but to a significant
  • degree in only 22 %.

  • Recently acne scars have been classified into three types: icepick,

  • rolling, and boxcar. Various treatment modalities are used for reconstructing
  • and improving the appearance of acne scars, including punch excision,
  • punch elevation, subcutaneous incision (subcision), chemical
  • skin resurfacing, and laser skin resurfacing. By combining
  • these multiple modalities, it is possible to produce dramatic
  • improvement in acne scars.lS However, procedures that include chemical
  • skin resurfacing have generally been limited to skin types N-VJ.9
  • So far, no appropriate and effective single treatment modality has
  • been developed for reconstructing and ameliorating the appearance
  • of acne scars.

  • Most surgeons want to use higher TCA concentrations because they

  • produce increased dermal thickening and collagen volume.7 However,
  • such use results in resurfacing difficulties and can produce severe
  • scarring because of damage to the adjacent normal skin, although
  • severe scarring usually does not occur in resurfacing with
  • lower TCA concentrations because of reepithelialization from hair
  • follicles and adjacent normal tissue that were spared from
  • chemical damage. So peeling with higher TCA concentrations is very
  • risky and definitely not recommended.

  • We suggest the CROSS method, which consists of the focal application

  • of higher TCA concentrations, even up to 100%, by pressing hard
  • on the entire depressed area of atrophic acne scars using a
  • sharpened wooden applicator. This technique, achieved with higher
  • TCA concentrations of 65% or 100% TCA alone, has the great advantage
  • of reconstructing the acne scars by focusing on the dermal thickening
  • and collagen production that increases with high TCA concentrations.
  • Of interest is that rather than being equivalent to the classic
  • full-face chemical resurfacing, this technique can be used on focal
  • chemical scar reconstruction. Moreover, this technique can avoid
  • scarring and reduce the risk of developing hypopigmentation
  • by sparing the adjacent normal skin and adnexal structures.
  • We found that in using the CROSS method, application with 100%
  • TCA was more effective in treating atrophic acne scars than with
  • 65% TCA.

  • Repeated CROSS application can normalize deep rolling and boxcar

  • scars, and a similar result can be achieved for deep icepick scars
  • with higher TCA concentrations of up to 100%. Because clinical
  • improvement is proportional to the number of courses of CROSS
  • treatment, this method is effective for the treatment of all deep
  • acne scar types. Furthermore, it can also be utilized for autologous
  • soft tissue augmentation prior to performing the classic full-face
  • resurfacing modalities for deeply pitted areas.20 Also, we
  • have used this technique successfully for treating dilated
  • pores. Recently we used the CROSS method for reconstructing depressed
  • surgical scars.

  • No patient developed any significant complication such as persistent

  • erythema, permanent hyperpigmentation, hypopigmentation, scarring,
  • or keloids. The use of 100% TCA CROSS did not increase the frequency
  • of complications compared with 65% TCA CROSS. All cases of mild
  • erythema and transient postinflammatory hyperpigmentation faded
  • over 1-2 months and focal skin infections were cleared by oral antibiotics.
  • No herpes simplex flare-up occurred in the nine patients with a
  • positive history of herpes without oral antiviral prophylaxis.

  • A history of drugs that depress adnexal glands, such as isotretinoin,

  • is a relative contraindication tomedium to deep chemical resurfacing
  • because of the increased risk of developing hypertrophic scars.3
  • We believe that a drug history of isotretinoin is not a relative
  • contraindication and does not influence the clinical results
  • because CROSS may spare the adjacent normal skin. But further study
  • is required to determine the effect of isotretinoin in CROSS.

  • We conclude that the CROSS method presented in this study is a

  • safe and very effective single modality for the treatment of atrophic
  • acne scars with no significant complications. The degree of
  • clinical improvement was proportional to the number of courses
  • of CROSS treatment, with good improvement after three to six courses
  • being recorded in more than 90% of cases. Most patients, 82% in
  • the 65% TCA group and 94% in the 100% TCA group, were satisfied
  • with the CROSS method. Furthermore, the CROSS method with 100% TCA
  • was more effective in treating atrophic acne scars than with
  • 65% TCA.

    This Scar Remover Solution should not be applied to the whole face or body part but only on localized scars using a Q-tip or a tooth pick for 3 minutes only. Then rinse with soap and water.

    Do not apply to the wfole face but small scars only. Keep away from children. Do not taste or swallow. 

    This

  • peel is not recommended for patients with: inflammatory process in the
  • area to be treated, re-occurring herpes infections, pregnancy (
  • confirmed or suspected), sun related activities and mental problems.

  • AGREEMENT: 
  • You agree to indemnify and hold harmless Anais Corporation,
  • www.ezpeel.net, its officers, employees, agents, and suppliers from and
  • against any and all claims, charges, demands, damages, liabilities,
  • losses, expenses, and liabilities of whatever nature and howsoever
  • arising (including but not limited to any legal or other professional
  • fees and the costs of defending or prosecuting any claim and any other
  • direct or consequential loss) incurred or suffered directly or
  • indirectly as a result of using any product listed on our website.

    Buyer and user must wear a Sunblock after the peel for several months.



Average Customer Review: Based on 3 reviewsWrite a review

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  0 of 1 people found the following review helpful:
 
Super produit. November 2, 2009
Reviewer: Karine Mechin from Monaco  
Tres impressioner, les resultas sont fabuleux, j'en parelerai a mes amis.

Thank you for your feedback on this review. We appreciate your input!

  0 of 0 people found the following review helpful:
 
Great product August 15, 2009
Reviewer: Dr. Marco Desantos from New York, NY  
Great results on scars.

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  0 of 1 people found the following review helpful:
 
Excellent products! November 22, 2008
Reviewer: Rita from Miami, FL United States  
Works really well om pitted scars, thank you so much!!!!

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