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Scar Remover Kit

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Product Code: SCARS1

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Instructions

Ingredients

0.5 ounces sealed bottle. This kit is good for about 50 scars.
EXCELLENT for: Pitted scars, Scars, Acne scars, Rolling scars.

Features

TCA cross method used by plastic surgeons & dermatologists worldwide
-Pitted scars
-Scars
-Acne scars
-Rolling scars

BACKGROUND: Acne
scarring is a common complication of acne and yet no appropriate
and effective single treatment modality has been developed.
We suggest a technique consisting of the focal application of higher
trichloroacetic acid (TCA) concentrations by pressing hard
on the entire depressed area of atrophic acne scars. This technique
is called chemical reconstruction of skin scars (CROSS) by
the authors.
OBJECTIVE: To evaluate the clinical effects of
CROSS on atrophic acne scars in dark-complexioned patients.
METHODS: An analysis was conducted of 65 patients
with atrophic acne scars who were treated with CROSS in our
hospitals between July 1996 and July 2001. Thirty-three patients
were treated with 65% TCA CROSS and 32 patients were treated with
100% TCA CROSS. All patients had Fitzpatrick skin types N-V.
RESULTS: Patient treatment data indicated that
27 of 33 patients (82%) (the 65% TCA group) and 30 of 32 patients
(94%) (the 100% TCA group) experienced a good clinical response.
All patients in the 100% TCA group who received five or six courses
of treatment showed excellent results. Good satisfaction rates
in the 65% and 100% TCA groups were re_ corded. There were no cases
of significant complication.
CONCLUSION: CROSS is a safe and very effective
single modality for the treatment of atrophic acne scars with
no significant complications.
J. B. LEE, MD, W. G. CHUNG, MD, H.
KWAHCK, MD, AND K. H. LEE, MD HAVE INDICATED NO SIGNIFICANT INTEREST
WITH COMMERCIAL SUPPORTERS.
TRICHLOROACETIC ACID (TCA) has a particularly long history as an
effective agent for rendering histologic and clinical improvement
to the skin and is particularly safe when used as a superficial
peel or in "combination peels" of medium depth for acne
scars.l-4 Application of TCA to the skin causes precipitation of
proteins and coagulative necrosis of cells in the epidermis
and necrosis of collagen in the papillary to upper reticular dermis.1
Over several days the necrotic layers slough and the skin reepithelializes
from the adnexal structures that were spared from chemical damage.3
Dermal collagen remodeling after chemical peel may continue for
several months.4 Many investigators have observed that the clinical
effects of TCA were due to both a reorganization in dermal structural
elements and an increase in dermal volume as a result of an increase
in collagen content, glycosaminoglycan, and elastin.
Recent studies have shown that the reticular dermis heals with
scarring. They offer an explanation for some of the increased risk
associated with the use of TCA for deeper peels, suggesting that
peeling with higher TCA concentrations is very risky and definitely
not recommended.8 We also have limited experience and very little
information regarding the effects of higher TCA concentrations for
acne scars in darkcomplexioned patients, including Koreans
(types IVVI), whose skin is known to develop postinlammatory
hyperpigmentation.
In order to maximize the effects of TCA and to overcome complications
such as scarring, hyperpigmentation, and hypopigmentation,
we suggest a technique consisting of the focal application
of higher TCA concentrations by pressing hard on the entire depressed
area of atrophic acne scars using a sharpened wooden applicator
(Figure 1).11 Eventually it produces multiple, frosted white spots
on each acne scar (Figure 2). This technique is called chemical
reconstruction of skin scars (CROSS) by the authors; however, the
technique itself has not been patented or restricted to prevent
usage. The CROSS method, achieved with 65% or 100% TCA alone, has
the advantage of reconstructing acne scars by focusing on the
dermal thickening and collagen production that increase with high
TCA concentrations.7 Healing is more rapid and has a lower complication
rate than conventional full-face medium to deep chemical resurfacing,
because the adjacent normal tissue and adnexal structures are
spared. This technique does not involve the classic full-face
chemical resurfacing, but rather it can be used on focal chemical
scar reconstruction. We have used this technique successfully
for treating facial acne scars and dilated pores for the past 10
years. The purpose of this study was to evaluate the clinical effects
of the CROSS method on atrophic acne scars in dark-complexioned
patients.
Materials and Methods:
An analysis was conducted of 65 patients with atrophic
acne scars who were treated with the CROSS method in our hospitals
between July 1996 and July 2001. The CROSS method consists of the
focal application of higher TCA concentrations by pressing
hard on the entire depressed area of atrophic acne scars using a
sharpened wooden applicator (Figure 1). TCA, 65-100% weight/volume,
unbuffered, was made to order by a local pharmacy.
The patients' ages ranged from 25 to 45 years (mean 32.5 years).
Fifty-five patients were women and 10 were men. All patients had
Fitzpatrick skin types IV-V. Thirtythree patients were treated
with 65% TCA CROSS and 32 with 100% TCA CROSS.
For independent clinical assessment, two blinded physicians
evaluated the photographs taken before treatment and 6 months after
completion of the treatment. Physicians categorized the improvement
as follows: excellent, improvement greater than 70%; good, improvement
of 50-70%; fair, improvement of 30-50%; poor, improvement less
than 30%. The patient satisfaction rates were recorded from the
interviews conducted 6 months after the last treatment. The
physicians evaluated complications such as persistent erythema,
permanent hyperpigmentation, hypopigmentation, herpes simplex flare-up,
scarring, or keloids.
Patients were evaluated carefully before treatment about the factors
considered important, including the patients' current and past medications
and active acne lesion. Relevant history was obtained, including
any history of prior hypertrophic scarring, keloids, allergies,
or herpes simplex infection. Before CROSS, pretreatments such
as tretinoin cream were not applied because of the risk of unpredictable
and excessive TCA penetration.
Local anesthetics or sedation were not needed for CROSS. Patients
were comfortable during the procedure. After facial washing with
soap, the skin was cleansed with alcohol. And then either 65% TCA
or 100% TCA was focally applied by pressing hard on the entire depressed
area of atrophic acne scars using a sharpened wooden applicator
(Figure 1). The skin was monitored carefully until it reached a
"frosted" appearance after a single application.
The frosted appearance is the result of coagulation of epidermal
and dermal proteins and is used mainly to monitor the peel depth.
Focal application of TCA produced even frosted spots on each
acne scar within 10 seconds (Figure 2). After CROSS, an ointment
based antibiotic instead of an occlusive dressing was applied for
moisturizing effect, but this application was discontinued after
crust formation in order to avoid the risk of detaching the crust.
Oral prophylaxis consisting of antibiotics and antiviral medications
were not needed after CROSS. One to 2 weeks after CROSS, a moisturizer
sunscreen cream consisting of 0.05% tretinoin, 5% hydroquinone,
and a hydro base was used in some patients for a minimum of 4 weeks.
The application of makeup was allowed after CROSS. CROSS was
repeatedly performed every 1-3 months to allow dermal thickening
and collagen production.
Results:
The patient treatment data indicated that 27 of 33 patients
(82%) (the 65% TCA group) and 30 of 32 patients (94%) (the
100% TCA group) experienced a good clinical response (Table 1).
In the 65% TCA group, 15 of 15 patients (100%) who received more
than six courses of treatment demonstrated good or excellent results,
as did 2 of 5 patients (40%) who received treatment three times
(Table 1 and Figure 3). Of interest is that all patients in the
100% TCA group who received five or six courses of treatment showed
excellent results (Table 1 and Figure 4). Table 1 shows that the
clinical effects of 100% TCA CROSS were better than those of 65%
TCA CROSS.
Good satisfaction rates in the 65% and 100% TCA groups were recorded
in 27 of 33 patients (82%) and 30 of 32 patients (94%), respectively
(Table 2). In the 65% TCA group, 16 of 33 patients (49%) and 11
of 33 patients (33 %) were satisfied with this therapy absolutely
and moderately, respectively (Table 2). In the 100% TCA group, 19
of 32 patients (59%) and 11 of 34 patients (34%) were satisfied
absolutely and moderately, respectively (Table 2).
There were no cases of significant complication at the treatment
sites such as persistent erythema, permanent hyperpigmentation,
hypopigmentation, herpes simplex flare-up, scarring, or keloids.
Relative to the 65% TCA CROSS treatment, 100% TCA CROSS did not
increase the frequency of complications. Only mild erythema, which
faded over 2-8 weeks, and transient postinflammatory hyperpigmentation,
which disappeared over 6 weeks, occurred. Mild pustular eruptions
occurred in only four patients and cleared within 1 week with the
use of cefadroxil500 mg three times a day. The two patients who
received isotretinoin for 3 months before treatment showed good
results without excessive scarring, although it should be noted
that full-face medium to deep chemical resurfacing is relatively
contraindicated in patients who have taken isotretinoin within the
previous 6 months because of the increased risk of hypertrophic
scarring.
The results indicated that higher treatment frequency of CROSS
application on acne scars improved the therapeutic effect, and there
were no significant complications. Furthermore, application of a
higher TCA concentration was more effective in the treatment
of atrophic acne scars.
Discussion:
Acne is a chronic inflammatory disease of the pilosebaceous unit
and a condition commonly experienced in adolescents, but recent
data indicate that the prevalence of clinical acne does not
show a significant decrease in women between the ages of 25
and 44 years.12 Acne scars are more common in this persistent acne
group, because acne scars correlate with the duration of acne. Minor
acne scarring may occur in up to 95% of patients, but to a significant
degree in only 22 %.
Recently acne scars have been classified into three types: icepick,
rolling, and boxcar. Various treatment modalities are used for reconstructing
and improving the appearance of acne scars, including punch excision,
punch elevation, subcutaneous incision (subcision), chemical
skin resurfacing, and laser skin resurfacing. By combining
these multiple modalities, it is possible to produce dramatic
improvement in acne scars.lS However, procedures that include chemical
skin resurfacing have generally been limited to skin types N-VJ.9
So far, no appropriate and effective single treatment modality has
been developed for reconstructing and ameliorating the appearance
of acne scars.
Most surgeons want to use higher TCA concentrations because they
produce increased dermal thickening and collagen volume.7 However,
such use results in resurfacing difficulties and can produce severe
scarring because of damage to the adjacent normal skin, although
severe scarring usually does not occur in resurfacing with
lower TCA concentrations because of reepithelialization from hair
follicles and adjacent normal tissue that were spared from
chemical damage. So peeling with higher TCA concentrations is very
risky and definitely not recommended.
We suggest the CROSS method, which consists of the focal application
of higher TCA concentrations, even up to 100%, by pressing hard
on the entire depressed area of atrophic acne scars using a
sharpened wooden applicator. This technique, achieved with higher
TCA concentrations of 65% or 100% TCA alone, has the great advantage
of reconstructing the acne scars by focusing on the dermal thickening
and collagen production that increases with high TCA concentrations.
Of interest is that rather than being equivalent to the classic
full-face chemical resurfacing, this technique can be used on focal
chemical scar reconstruction. Moreover, this technique can avoid
scarring and reduce the risk of developing hypopigmentation
by sparing the adjacent normal skin and adnexal structures.
We found that in using the CROSS method, application with 100%
TCA was more effective in treating atrophic acne scars than with
65% TCA.
Repeated CROSS application can normalize deep rolling and boxcar
scars, and a similar result can be achieved for deep icepick scars
with higher TCA concentrations of up to 100%. Because clinical
improvement is proportional to the number of courses of CROSS
treatment, this method is effective for the treatment of all deep
acne scar types. Furthermore, it can also be utilized for autologous
soft tissue augmentation prior to performing the classic full-face
resurfacing modalities for deeply pitted areas.20 Also, we
have used this technique successfully for treating dilated
pores. Recently we used the CROSS method for reconstructing depressed
surgical scars.
No patient developed any significant complication such as persistent
erythema, permanent hyperpigmentation, hypopigmentation, scarring,
or keloids. The use of 100% TCA CROSS did not increase the frequency
of complications compared with 65% TCA CROSS. All cases of mild
erythema and transient postinflammatory hyperpigmentation faded
over 1-2 months and focal skin infections were cleared by oral antibiotics.
No herpes simplex flare-up occurred in the nine patients with a
positive history of herpes without oral antiviral prophylaxis.
A history of drugs that depress adnexal glands, such as isotretinoin,
is a relative contraindication tomedium to deep chemical resurfacing
because of the increased risk of developing hypertrophic scars.3
We believe that a drug history of isotretinoin is not a relative
contraindication and does not influence the clinical results
because CROSS may spare the adjacent normal skin. But further study
is required to determine the effect of isotretinoin in CROSS.
We conclude that the CROSS method presented in this study is a
safe and very effective single modality for the treatment of atrophic
acne scars with no significant complications. The degree of
clinical improvement was proportional to the number of courses
of CROSS treatment, with good improvement after three to six courses
being recorded in more than 90% of cases. Most patients, 82% in
the 65% TCA group and 94% in the 100% TCA group, were satisfied
with the CROSS method. Furthermore, the CROSS method with 100% TCA
was more effective in treating atrophic acne scars than with
65% TCA.
This Scar Remover Solution should not be applied to the whole face or body part but only on localized scars using a Q-tip or a tooth pick for 3 minutes only. Then rinse with soap and water.
Do not apply to the wfole face but small scars only. Keep away from children. Do not taste or swallow.
This
peel is not recommended for patients with: inflammatory process in the
area to be treated, re-occurring herpes infections, pregnancy (
confirmed or suspected), sun related activities and mental problems.
AGREEMENT:
You agree to indemnify and hold harmless Anais Corporation,
www.ezpeel.net, its officers, employees, agents, and suppliers from and
against any and all claims, charges, demands, damages, liabilities,
losses, expenses, and liabilities of whatever nature and howsoever
arising (including but not limited to any legal or other professional
fees and the costs of defending or prosecuting any claim and any other
direct or consequential loss) incurred or suffered directly or
indirectly as a result of using any product listed on our website.

Buyer and user must wear a Sunblock after the peel for several months.

Average Customer Review: Based on 3 reviewsWrite a review

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0 of 1 people found the following review helpful:

Super produit.	November 2, 2009
Reviewer: Karine Mechin from Monaco

Tres impressioner, les resultas sont fabuleux, j'en parelerai a mes amis.

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0 of 0 people found the following review helpful:

Great product	August 15, 2009
Reviewer: Dr. Marco Desantos from New York, NY

Great results on scars.

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0 of 1 people found the following review helpful:

Excellent products!	November 22, 2008
Reviewer: Rita from Miami, FL United States

Works really well om pitted scars, thank you so much!!!!

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